Examining the Associations between Post-Stroke Cognitive Function and Common Comorbid Conditions among Stroke Survivors.

A considerable complication for stroke survivors is the subsequent development of cognitive decline or dementia. In this study, the relationship between the inflammation-centered comorbidity burden on post-stroke cognitive function among community-dwelling stroke survivors capable of independent living was examined. Data for this secondary analysis were collected from stroke survivors (n = 97) participating in a randomized clinical trial. Participants provided baseline responses, regarding cognitive function (mini-mental status exam, MMSE; Montreal cognitive assessment, MoCA), history of stroke comorbid conditions, and the Stroke Prognosis Instrument-II (SPI-II), an index of stroke comorbidity and recurrent stroke risk within the next two years. Relationships and differences between groups were tested for significance using Spearman's correlation, Kruskal-Wallis, or Mann-Whitney U tests. Most stroke survivors (69%) had multiple comorbidities. Total SPI-II scores were negatively correlated to both MoCA and MMSE scores (r = -0.25, p = 0.01; r = -0.22, p = 0.03, respectively), and differences in MoCA scores among SPI-II risk groups (low, medium, high) were evident (p = 0.05). In contrast, there were no differences in MoCA or MMSE scores when comorbid conditions were examined individually. Lastly, no gender differences were evident in cognitive assessments. Our data support the premise that comorbidity's burden impacts post-stroke cognitive decline, more than a single comorbid condition. Inflammation may be an important component of this comorbidity burden. Future studies that operationalize this concept will better illuminate the complex phenomenon of post-stroke cognitive decline for improved clinical rehabilitation modalities.

Effects of stretching on muscle activation in gas cylinder handling.

BACKGROUND: Previously, a stretching regimen was designed for manual material handling (MMH) of gas cylinders as a potential ergonomic solution for reducing occupational injury. No studies have made use of objective process measures, such as muscle activation levels, for evaluation of effects of stretching programs. OBJECTIVE: Examine acute effects of stretching on muscle activation levels and driver perceived level of exertion in gas cylinder handling during simulated delivery operations. METHODS: A within-subject experiment was conducted with eight male participants being subjected randomly to two conditions over a two-day period: stretching before delivery trials and no stretching. Surface electromyography and the Borg CR-10 scale for perceived exertion were used. RESULTS: Generally, results were variable among muscle responses. The extensor muscle bundle in the forearm was found to show a significant decrease (p = 0.0464) in activation level because of stretching. The anterior deltoid and trapezius significantly increased (p < .0001) the EMG activation level with stretching. Also counter to expectations, participants rated perceived exertion significantly higher (p = 0.0423) for trials preceded by stretching. CONCLUSIONS: This research indicates a muscle stretching regimen in advance of MMH activities has mixed effects on activation levels across muscles. It is possible that effects are attributable to body posture positions, or manner of muscle use, during actual work activities. Findings indicate that stretching prior to work activity does have an impact on specific muscle activation.

Muscle loading in exoskeletal orthotic use in an activity of daily living.

Strokes are the leading cause of major adult disability with up to 85% of U.S. survivors experiencing hemiparesis. Physical characteristics of upper-extremity exoskeletal orthotics, used in stroke rehabilitation, were evaluated in terms of performance of activities of daily living (ADL), perceived exertion, and muscle load. Simulated orthotic weight distributions, with total extremity loads of 0.81 kg, 1.25 kg and 2.27 kg, were evaluated along with a 0 kg control condition. Response measures included average shoulder/elbow muscle surface electromyography (sEMG) signal amplitude, quality of task completion and total rest time during performance, and Borg CR-10 scale ratings. Device weight distribution, or imposed shoulder moment, was found to have a significant effect on biceps brachii and anterior deltoid activation levels, percent task completion, total rest time, and perceived exertion ratings. Results suggest that heavier upper-extremity orthotics could cause undesirable effects in terms of muscle loading, performance and exertion; such adverse effects could potentially lead to lack of use during patient's rehabilitation.

Using the Assessment for Signal Clients as a feedback tool for reducing treatment failure.

OBJECTIVE: The Clinical Support Tools (CSTs) were developed to help therapists organize and target potential problems that might account for negative outcomes in psychotherapy. The core of CST feedback is the Assessment for Signal Clients. The purpose of this study was to describe and identify patterns of problems that typically characterize off-track cases. METHOD: The responses and scores from 107 off-track clients from a hospital-based outpatient clinic were analyzed. RESULTS: A cluster analysis of the 107 off-track clients revealed three client types: those whose problems were characterized by alliance and motivational difficulties; those characterized by social support and life event difficulties; and those whose problems had an indistinguishable pattern. Log-linear modeling showed that if patients had less therapeutic alliance problems they were also less likely to have motivational problems. Findings were also consistent with the cluster analysis, which showed that a relatively higher percentage of not-on-track participants received signal alerts for the social support items and scale. CONCLUSIONS: Individuals whose progress goes off-track while in psychotherapy appear to have their greatest difficulty with social support, followed closely by motivation for therapy and therapeutic alliance.